A wide variety of kinds of cancers that exist, but this one is a rare disease including cancer. Cancer of the spine is also called or Myxopapillary ependymoma. Are tumors that arise from the ependyma, the central nervous system tissue. Usually, in children the intracranial location, whereas in adults it is the spine. General location of intracranial ependymoma is the fourth ventricle. Rarely, ependymoma can occur in the pelvic cavity.
Myxopapillary ependymomas are slow-growing tumor that manifests almost exclusively in the conus-cauda-phylum terminale young adults. These tumors are histologically characterized by neoplastic cells arranged around vascularized stromal cores papillar slimy. This disease involves the Conus and cauda equina. Spontaneous pain that occur are usually associated with the Conus, whereas the most prominent symptoms occur in patients usually occurs in the cauda equina. Cauda equina pain involving the thigh and leg.
Patients sometimes experience a sensory decrease in injuries (lesions) in the cauda equina. While autonomic dysfunction such as decreased bladder function, and impotence is an early symptom of the injury (lesion) Conus medullaris. Patients who had tumors in the spine Conus and cauda equina can have a combination of symptoms. When these tumors grow, leg paralysis, leg muscle atrophy and decreased function of the foot. If the condition is getting worse, can make patients unable to move his limbs.
The development begins with the growth of cancer cells plasma cells, which is one part of the white blood cells in bone marrow that is not normal. Plasma cells in normal conditions it is necessary, because it produces proteins called antibodies, as part of the immune system. These abnormal plasma cells in marrow is not only silent, but also on other body parts, and often found in the pelvis, ribs, and skull-because it is called multiple myeloma. Antibodies produced increases too.
Abnormal antibodies that had accumulated in the blood or urine, sometimes found also in areas other than bone, such as the lungs and reproductive organs. Fraction of abnormal antibodies (Bence-Jones protein) is often collected in the kidneys, damaging and lead to kidney failure.
In addition, patients experience anemia, since normal cells producing red blood cells in the spinal cord is replaced by abnormal cells. Which thickens the blood (hyperviscosity syndrome) also can affect blood flow to the brain, skin, fingers and toes, and nose.
Myxopapillary ependymomas are slow-growing tumor that manifests almost exclusively in the conus-cauda-phylum terminale young adults. These tumors are histologically characterized by neoplastic cells arranged around vascularized stromal cores papillar slimy. This disease involves the Conus and cauda equina. Spontaneous pain that occur are usually associated with the Conus, whereas the most prominent symptoms occur in patients usually occurs in the cauda equina. Cauda equina pain involving the thigh and leg.
Patients sometimes experience a sensory decrease in injuries (lesions) in the cauda equina. While autonomic dysfunction such as decreased bladder function, and impotence is an early symptom of the injury (lesion) Conus medullaris. Patients who had tumors in the spine Conus and cauda equina can have a combination of symptoms. When these tumors grow, leg paralysis, leg muscle atrophy and decreased function of the foot. If the condition is getting worse, can make patients unable to move his limbs.
The development begins with the growth of cancer cells plasma cells, which is one part of the white blood cells in bone marrow that is not normal. Plasma cells in normal conditions it is necessary, because it produces proteins called antibodies, as part of the immune system. These abnormal plasma cells in marrow is not only silent, but also on other body parts, and often found in the pelvis, ribs, and skull-because it is called multiple myeloma. Antibodies produced increases too.
Abnormal antibodies that had accumulated in the blood or urine, sometimes found also in areas other than bone, such as the lungs and reproductive organs. Fraction of abnormal antibodies (Bence-Jones protein) is often collected in the kidneys, damaging and lead to kidney failure.
In addition, patients experience anemia, since normal cells producing red blood cells in the spinal cord is replaced by abnormal cells. Which thickens the blood (hyperviscosity syndrome) also can affect blood flow to the brain, skin, fingers and toes, and nose.
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